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Sinemet Medication - Uses & Side Effects

Sinemet® CR is used to treat Parkinson's disease. It help correct an imbalance of chemicals in the brain that may be cause by Parkinson's disease. Sinemet CR contains two drugs such as carbidopa and levodopa. Carbidopa prevents vitamin B6 from destroying levodopa, thus allowing levodopa to work more efficiently.

Sinemet CR Dosage

  • For the treatment of mild to moderate symptoms, the usual starting dose is 1 tablet of Sinemet CR and you should be taken 2 times a day.
  • The usual starting long-term dose is 2 to 8 tablets per day, taken in divided doses every 4 to 8 hours during the waking day.

Uses of Sinemet CR

  • This medication is used to treat symptoms of Parkinson's disease.
  • It may also be used to treat other medical conditions those are listed in the medication guide.

Side Effects of Sinemet CR

Before taken Sinemet CR medicine, you should discuss the side effects with your doctor.  If any develop or change in intensity, then you should inform your doctor as soon as possible. Because only your doctor can determine if it is safe for you to continue taking Sinemet CR. Side effects may include:

  • Confusion
  • Hallucinations
  • Nausea
  • Uncontrollable twitching or jerkin
  • Bleeding from stomach
  • Chest pain

Warnings and precautions before taking Sinemet CR:

  • You should not be stopped taking this medicine without talking with your doctor.
  • If you feel depressed or confused, or have strange while you are taking this medicine, then you should contact with your doctor immediately.
  • After taken this medicine, then you may feel dizzy, or drowsiness. So you should not participate in any activities that require alertness such as driving and operate machinery.

Drug Interaction :-

If you are taking Sinemet CR with certain other drugs, then the effects of either could be increased, decreased, or altered. So it is especially important to check with your doctor before combining Sinemet CR with the following:

  • Antacids such as Di-Gel, Maalox, and Mylanta
  • High-protein foods
  • Isoniazid
  • Major tranquilizers such as Haldol, Mellaril, Risperdal, and Thorazine
  • Metoclopramide
  • Papaverine
  • Tricyclic antidepressants such as Elavil and Tofranil

Too much Sinemet CR may cause muscle twitches, inability to open the eyes. So after taken Sinemet CR if you feel that overdose is suspected, then you should contact with your doctor immediately. Because it may lead to another serious effect.

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