Gyne Lotrimin

Depo-Provera Medication - Uses & Side Effects

medroxyprogesterone (injectable)
Pronunciation: meh drock see pro JESS te rone
Brand: Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104

Depo-Provera is a drug that very similar to progesterone, a hormone normally produced by the ovaries every month as part of the menstrual cycle. It is an injectable medicine that prevents pregnancy for up to 3 months with each injection.

Depo-Provera Dosage

Depo-Provera is given as a single 150-milligram injection every 3 months (13 weeks).

Uses of Depo-Provera

  • Depo-Provera is also used in the treatment of certain cancers such as cancer of the endometrium and kidney cancer.
  • Medroxyprogesterone is used as a contraceptive to prevent pregnancy.

Side Effects of Depo-Provera

Before taken Depo-Provera medicine, you should discuss the side effects with your doctor.  If any develop or change in intensity, then you should inform your doctor as soon as possible. Because only your doctor can determine if it is safe for you to continue taking Depo-Provera. Side effects may include:

  • Abdominal pain or discomfort
  • Dizziness
  • Headache
  • Nervousness
  • Unpredictable menstrual bleeding
  • Weakness or fatigue

Warnings and precautions before taking Depo-Provera

  • Depo-Provera may be cause fluid retention, so if you have any medical conditions that may be worsened by fluid retention, such as epilepsy, migraine headaches, asthma, or kidney disease, then you should tell your doctor immediately.
  • If you develop jaundice, then you should not take Depo-Provera again.
  • Before you start using Depo-Provera, you should tell your doctor if you or anyone in your family has ever had breast cancer; or if your menstrual periods have ever been irregular or spotty; if you or anyone in your family has or has had diabetes; or if you are taking any prescription or over-the-counter drugs.
  • Do not take Depo-Provera medication if you are pregnant, as this medicines can cause birth defects in an unborn baby.

Drug Interaction :-

If you are taking Depo-Provera with certain other drugs, then it may be increased, decreased, or altered the effects of medicine. If Depo-Provera is taken with aminoglutethimide (Cytadren), a drug that used to treat a disorder of the adrenal glands known as cushing's syndrome, it could make the Depo-Provera less potent, which could lead to unexpected pregnancy. So it is especially important to check with your doctor before combining Depo-Provera with other drugs.


An overdose of Depo-Provera is highly unlikely. But after taken Depo-Provera if you feel that overdose is suspected, then you should contact with your doctor immediately. Because it may lead to another serious effect.

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