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Chlorpromazine Medication- Uses & Side Effects

Chlorpromazine is in a class of drugs known as phenothiazines. It works by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is a natural compound known as neurotransmitter, and it is involved in transmitting messages between brain cells.

Chlorpromazine Dosage

  • For the treatment of Nausea and Vomiting, the usual starting dosage is 10 to 25 milligrams, and you should be taken every 4 or 6 hours.
  • For the treatment of Uncontrollable Hiccups, the usual starting dosages range from 75 to 200 milligrams daily.

Uses of Chlorpromazine

  • Chlorpromazine is used for various types of mental or emotional conditions.
  • It is also used to control hiccups, reduce anxiety and treat nausea and vomiting.

Side Effects of Chlorpromazine

Before taken Chlorpromazine medicine, you should discuss the side effects with your doctor. If any develop or change in intensity, then you should inform your doctor as soon as possible. Because only your doctor can determine if it is safe for you to continue taking Chlorpromazine. Side effects may include:

  • Constipation
  • Drowsiness
  • Involuntary muscle spasms and twitches
  • Jaundice
  • Low blood pressure
  • Neuroleptic malignant syndrome
  • Rapid heartbeat
  • Restlessness

Warnings and precautions before taking Chlorpromazine:

  • If you suddenly stop taking chlorpromazine, then it may cause stomach inflammation, nausea, vomiting, and tremors may result.
  • You should tell your doctor if you are allergic to chlorpromazine, any other tranquilizer, or any other drugs, or have had a bad reaction to insulin.
  • If you are taking prescription and nonprescription medications especially antihistamines; lithium; medications for depression, Parkinson's disease, seizures, hay fever, allergies, or colds, then you should tell your doctor.
  • You should tell your doctor if you have heart, liver, lung, or kidney disease; shock therapy; difficulty urinating; asthma, or seizures.

Drug Interaction :-

If you are taking Chlorpromazine with certain other drugs, then the effects of either could be increased, decreased, or altered. So it is especially important to check with your doctor before combining Chlorpromazine with the following:

  • Anesthetics
  • Barbiturates such as phenobarbital
  • Captopril
  • Diuretics such as Dyazide
  • Epinephrine
  • Guanethidine
  • Lithium
  • MAO inhibitors
  • Narcotics such as Percocet
  • Propranolol

After taken Chlorpromazine if you feel that overdose is suspected, then you should contact with your doctor immediately. Because it may lead to another serious effect. Symptoms of a Chlorpromazine overdose include

  • Agitation
  • Coma
  • Difficulty breathing
  • Extreme sleepiness
  • Fever
  • Intestinal blockage
  • Irregular heart rate
  • Restlessness

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